Epilepsy Therapeutics in Major Developed Market expand at a total CAGR of over 3.3% to cross over $4.2 billion over the forecast period till 2019: Radiant Insights, Inc.

In 2012, the overall industry for epilepsy therapeutics in the major developed markets contributed for an approximate share of over $3.1 billion.  Furthermore, this market is anticipated to expand at a total CAGR of over 3.3% to cross over $4.2 billion over the forecast period till 2019. 

Epilepsy is described by recurring seizures as it is a set of long-term neurological disorders.  When a group of neurons in brains or nerve cells send wrong signals, episodes of these seizures occur. Depending on the cause of the epilepsy, seizures may possibly be different from primary comprehensive seizures to partial seizures. Patients suffering from epilepsy act weirdly and grumble about strange sensations and emotions. People of all ages are being affected by epilepsy as it is the fourth most common disorder. Doctors prescribe drugs or antiepileptic medicines for the treatment of epilepsy. It depends on the age of the patient seriousness of the seizures and type of seizures to be treated

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Recent approvals of drugs coupled with novel technologies of action are some of the factors attributing to the industry growth of the market. The U.S region contributes to the major market share for over 55% for the total market. In addition, three new anti-epileptic drugs have been permitted in the aforementioned region since 2012.  Fycompa, Trobalt and Aptiom are also projected to be launched over the coming years. Moreover, brivaracetam is likely to approve over the coming years.  Factors such as improved safety and tolerability of fycoma and trobalt are also contributing significantly owing to the increased interest of prescribers over the past few years.

Constant uptake of anti-epileptic drugs of second and third generation is anticipated to attribute towards the revenues in these regions.  Although, the market could experience the hindering impact of geriatric competition as a result of novel patent expiries in all the key industries especially for key branded drugs like Lamictal and Keppra.

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Key market players operating for epilepsy therapeutics in the major developed markets are Novartis AG, GlaxoSmithKine plc, Shire, Johnson & Johnson Pfizer,  Sanofi S.A, Cephalon, Abbot Laboratories, Sunovion Pharmaceuticals, Shire and Valeant Pharamceutical International Inc.

Table of Contents

Table of Contents 5

1.1 List of Tables 7

1.2 List of Figures 8

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2 Introduction 9

2.1 Disease Overview 9

2.2 Epidemiology 9

2.3 Symptoms 11

2.4 Etiology 11

2.5 Pathophysiology 12

2.6 Co-morbidities/Complications 12

2.7 Diagnosis 12

2.8 Prognosis 13

2.9 Treatment Efficacy 13

2.10 Treatment Options 14

2.10.1 Ion Channel Modulators 14

2.10.2 GABA-ergic Facilitation 15

2.10.3 Excitatory Amino Acid Inhibitors 15

2.10.4 Synaptic Modulators 15

2.11 Non-pharmacological Management 15

2.11.1 Lobectomy and Lesionectomy 15

2.11.2 Ketogenic Diet and Modified Atkins Diet 15

2.11.3 Vagus Nerve Stimulation 16

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